Project: Kalostasis
Partner: King’s College London
British Heart Foundation,
London Design Festival.

What if there was an exact replica of your internal physiology out there in the cloud, connected to the physiology of million
others? Big data now allow researchers to simulate our blood flow accurately.

As part of the Beyond Imaging project, Cellule have worked with Lucy Hardcastle studio and King’s College London to develop an interactive installation enacting the unseen flow of the heart: Kalostasis, that premiered at the London Design Festival at the V&A museum.




Medical imagery


3D Simulation
Technology research
Parametric design
Motion graphics



“The permanent
motion of blood
keeps us alive.”

The permanent motion of blood keeps us alive. Each day, our heart beats around 100,000 times and pumps about 2,000 litres of blood. The aorta, the largest artery in the body, is responsible for transporting blood to each and every cell.
Researchers at King’s College London are using MRI to visualise blood flow in 3D and accurately analyse it’s behavior in people with aortic stenosis, a condition which causes a narrowing of the aorta.

“Kalostasis is an interactive installation using 3D data from MRI Imaging.”

Kalostatis is an interactive installation enacting
the unseen flow of the heart. The installation is simulating in 360° the beauty and complexity of the constant flow and motion that keeps us alive, its various extremes and our body’s ability to attain a state of balance, an equilibrium key to our health.

The data has been translated from research into digital simulation in 3D of various flow conditions, and the extremes responses that could be found with big data research on several patients.

The concept of equilibrium within the heart flow can be found throughout nature, raising questions about the dynamic rhythms and flows that rules our world.

“Showing us heart flow turbulence with real time graphics and sensor tracking.”

With Kalostastis, we wanted to showcase in a large scale experience the connection between the micro and macro: audiences can literally step inside a human heart. It shows us the powerful and constant rhythm of the heart flow, using real-time rendered graphics, projection mapping and sensor tracking; and this based on the latest advancement in medical imagery.

The various extremes are linked to the audience presence, causing turbulence that have been witnessed in various anatomies. When viewers leave the structure, the simulation will gradually return to its neutral state, referencing the power and stamina of the heart.

Beyond Imaging is guided by the research of Dr. Pablo Lamata and his team at the School of Biomedical Engineering & Imaging Sciences at King’s College London. Their team is developing a new digital approach to healthcare creating a digital twin of the heart, it’s mechanics and physiology.

In partnership with ECHO charity, and the British Heart Foundation, this collaboration represents an innovative opportunity to work alongside scientific
institutions to challenge how we communicate, design and represent data that impacts our lives.

Project funded by King’s College London and the Wellcome Trust. Supported by British Heart Foundation and Evelina Children’s Heart Organisation

Co-Creative Directors – Lucy Hardcastle &
Salomé Bazin
Co-Producers – Lucy Hardcastle & Salomé
Scientific curator- Dr. Pablo Lamata
Scientific consultant- João Filipe Fernandes
Programmer – Will Young
Sound Designer – Thomas Rawle
Animation Designer – Thomas Rawle
Creative Consultant – Laura Vent
Photographer – Gareth Williams (project)
ECHO Charity photographs: Joel Virgov

Computational Cardiology

Big Data

Interactive Architecture

Computational cardiology is the use of advanced imaging, genetic screening and devices to understand heart conditions and to treat patients according to their specific pathophysiology. Cardiologists use computational models that analyse great amounts of patient-specific physiological and physical information, to reveal diagnostic information and predict clinical outcomes, which enables personalising treatment for individuals.
Scanning technologies (MRI, CT, Echocardiography) are widely used, non invasive technique to create detailed images of organs and tissue in the body using strong magnetic fields or ultrasound to create 2D or 3D imagery.

Big Data is the science of processing data that is too large, fast and complex to be analysed using traditional methods. With the advent of the internet and the internet of things, computers are dealing with extremely large quantities of data arriving in at an extremely fast rate and in a variety of complex formats (numbers, text, audio, video…). Big data seeks to capture, store and extract information from these kinds of data, with acceptable results and in an acceptable time. It englobes fields like statistical analysis and machine learning. Data analysis can help predict business trends, streamline user experiences, or build complex models of an individual’s hearts!
The paradigm shift in surgery is to plan the best healthcare provision adapted to our specific biological architecture and machinery. The combination of medical imagery with machine learning and omics science target for a better understanding of individuals as well as population health.

Interactive architecture is the art/science of creating spaces and buildings that interact with their visitors. By incorporating sensors, processors and effectors in the core of the architecture,we can create intelligent spaces that acquire the ability to gather information from the physical space, understand it and act in consequence on it. This allows architects to create a real-time, personalised interaction between a space and its visitors – between a smart object and a smart subject. For us designers, they become a vector for interactive art. We aim to create ‘spaces’ that respond to our presence and help us understand complex notions of the physical and natural world that we are constantly interacting with.